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Analysing the mutational status of PIK3CA in circulating tumor cells from metastatic breast cancer patients

The frequently altered phosphatidylinositol‐3‐kinase (PI3K)/Akt signaling pathway is involved in the regulation of cellular processes required for breast carcinogenesis. The aim of the project was to develop a method to identify hotspot mutations in the PIK3CA gene in circulating tumor cells (CTCs)...

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Détails bibliographiques
Publié dans:Mol Oncol
Auteurs principaux: Schneck, Helen, Blassl, Christina, Meier-Stiegen, Franziska, Neves, Rui Pedro, Janni, Wolfgang, Fehm, Tanja, Neubauer, Hans
Format: Artigo
Langue:Inglês
Publié: John Wiley and Sons Inc. 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5528457/
https://ncbi.nlm.nih.gov/pubmed/23895914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molonc.2013.07.007
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