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Genetically engineered mouse models of pancreatic adenocarcinoma

Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal types of human cancer for which there are no effective therapies. Deep sequencing of PDAC tumors has revealed the presence of a high number of mutations (>50) that affect at least a dozen key signaling pathways. This scenario highl...

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Dades bibliogràfiques
Publicat a:Mol Oncol
Autors principals: Guerra, Carmen, Barbacid, Mariano
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5528418/
https://ncbi.nlm.nih.gov/pubmed/23506980
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molonc.2013.02.002
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