Genetically engineered mouse models of pancreatic adenocarcinoma

Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal types of human cancer for which there are no effective therapies. Deep sequencing of PDAC tumors has revealed the presence of a high number of mutations (>50) that affect at least a dozen key signaling pathways. This scenario highl...

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Bibliografiske detaljer
Udgivet i:Mol Oncol
Main Authors: Guerra, Carmen, Barbacid, Mariano
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2013
Fag:
Special Papers
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5528418/
https://ncbi.nlm.nih.gov/pubmed/23506980
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molonc.2013.02.002
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