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Assaying the Effects of Splice Site Variants by Exon Trapping in a Mammalian Cell Line

There are several in silico programs that endeavor to predict the functional impact of an individual’s sequence variation at splice donor/acceptor sites, but experimental confirmation is problematic without a source of RNA from the individual that carries the variant. With the aid of an exon trappin...

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書目詳細資料
發表在:Bio Protoc
Main Authors: Tompson, Stuart W., Young, Terri L.
格式: Artigo
語言:Inglês
出版: Bio-Protocol 2017
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5528174/
https://ncbi.nlm.nih.gov/pubmed/28758139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21769/BioProtoc.2281
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