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Activation of direct and indirect pathway medium spiny neurons drives distinct brain-wide responses

A central theory of basal ganglia function is that striatal neurons expressing the D1 and D2 dopamine receptors exert opposing brain-wide influences. However, the causal influence of each population has never been measured at the whole-brain scale. Here, we selectively stimulated D1 or D2 receptor-e...

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Bibliographic Details
Published in:Neuron
Main Authors: Lee, Hyun Joo, Weitz, Andrew J., Bernal-Casas, David, Duffy, Ben A., Choy, ManKin, Kravitz, Alexxai V., Kreitzer, Anatol C., Lee, Jin Hyung
Format: Artigo
Language:Inglês
Published: 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5528162/
https://ncbi.nlm.nih.gov/pubmed/27373834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2016.06.010
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