Impact of disseminated neuroblastoma cells on the identification of the relapse-seeding clone

PURPOSE: Tumor relapse is the most frequent cause of death in stage 4 neuroblastomas. Since genomic information on the relapse precursor cells could guide targeted therapy, our aim was to find the most appropriate tissue for identifying relapse-seeding clones. EXPERIMENTAL DESIGN: We analyzed 10 geo...

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Veröffentlicht in:Clin Cancer Res
Hauptverfasser: Abbasi, M. Reza, Rifatbegovic, Fikret, Brunner, Clemens, Mann, Georg, Ziegler, Andrea, Pötschger, Ulrike, Crazzolara, Roman, Ussowicz, Marek, Benesch, Martin, Ebetsberger-Dachs, Georg, Chan, Godfrey C.F., Jones, Neil, Ladenstein, Ruth, Ambros, Inge M., Ambros, Peter F.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2017
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5528137/
https://ncbi.nlm.nih.gov/pubmed/28228384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-16-2082
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