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Expression of ToxR, the transcriptional activator of the virulence factors in Vibrio cholerae, is modulated by the heat shock response.

The toxR gene of Vibrio cholerae encodes a transmembrane, DNA-binding protein that positively controls transcription of the genes for cholera toxin, TCP pili, and other proteins important in cholera pathogenesis. Nucleotide sequence analysis of the toxR upstream region has revealed that the heat sho...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Parsot, C, Mekalanos, J J
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1990
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC55281/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2124707/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.87.24.9898
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