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HBx genotype D represses GSTP1 expression and increases the oxidative level and apoptosis in HepG2 cells

Epigenetics has been implicated in human cancer development. Epigenetic factors include HBx protein, which is able to induce hypermethylation and suppresses tumor suppressor genes. One of such tumor suppressor genes, GSTP1, shows reduced expression in many human cancers. Hypermethylation of GSTP1 is...

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Bibliografske podrobnosti
izdano v:Mol Oncol
Main Authors: Niu, Dandan, Zhang, Jianhua, Ren, Yudan, Feng, Huixing, Chen, Wei Ning
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2008
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5527876/
https://ncbi.nlm.nih.gov/pubmed/19383368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molonc.2008.10.002
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