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HBx genotype D represses GSTP1 expression and increases the oxidative level and apoptosis in HepG2 cells
Epigenetics has been implicated in human cancer development. Epigenetic factors include HBx protein, which is able to induce hypermethylation and suppresses tumor suppressor genes. One of such tumor suppressor genes, GSTP1, shows reduced expression in many human cancers. Hypermethylation of GSTP1 is...
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| 出版年: | Mol Oncol |
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| 主要な著者: | , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
John Wiley and Sons Inc.
2008
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5527876/ https://ncbi.nlm.nih.gov/pubmed/19383368 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molonc.2008.10.002 |
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