Full sequencing of TP53 identifies identical mutations within in situ and invasive components in breast cancer suggesting clonal evolution

In breast cancer, previous studies have suggested that somatic TP53 mutations are likely to be an early event. However, there are controversies regarding the cellular origin and linear course of breast cancer. The purpose of this study was to investigate tumor evolution in breast cancer by analyzing...

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Publicat a:Mol Oncol
Autors principals: Zhou, Wenjing, Muggerud, Aslaug A., Vu, Phuong, Due, Eldri U., Sørlie, Therese, Børresen-Dale, Anne-Lise, Wärnberg, Fredrik, Langerød, Anita
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2009
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Papers
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5527861/
https://ncbi.nlm.nih.gov/pubmed/19403344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molonc.2009.03.001
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