Mortality Associated with Bacteremia Due to Colistin-Resistant Klebsiella pneumoniae with High-Level Meropenem Resistance: Importance of Combination Therapy without Colistin and Carbapenems

Combination therapy including colistin and a carbapenem has been found to be associated with lower mortality in the treatment of bloodstream infections (BSI) due to KPC-producing Klebsiella pneumoniae when the isolates show a meropenem or imipenem MIC of <16 mg/liter. However, the optimal treatme...

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Veröffentlicht in:Antimicrob Agents Chemother
Hauptverfasser: Machuca, Isabel, Gutiérrez-Gutiérrez, Belén, Gracia-Ahufinger, Irene, Rivera Espinar, Francisco, Cano, Ángela, Guzmán-Puche, Julia, Pérez-Nadales, Elena, Natera, Clara, Rodríguez, Marina, León, Rafael, Castón, Juan J., Rodríguez-López, Fernando, Rodríguez-Baño, Jesús, Torre-Cisneros, Julián
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2017
Schlagworte:
Clinical Therapeutics
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5527651/
https://ncbi.nlm.nih.gov/pubmed/28559247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00406-17
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