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Signal Biosynthesis Inhibition with Ambuic Acid as a Strategy To Target Antibiotic-Resistant Infections

There has been major interest by the scientific community in antivirulence approaches against bacterial infections. However, partly due to a lack of viable lead compounds, antivirulence therapeutics have yet to reach the clinic. Here we investigate the development of an antivirulence lead targeting...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Todd, Daniel A., Parlet, Corey P., Crosby, Heidi A., Malone, Cheryl L., Heilmann, Kristopher P., Horswill, Alexander R., Cech, Nadja B.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5527603/
https://ncbi.nlm.nih.gov/pubmed/28607020
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00263-17
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