Heterocycle Thiazole Compounds Exhibit Antifungal Activity through Increase in the Production of Reactive Oxygen Species in the Cryptococcus neoformans-Cryptococcus gattii Species Complex

Human cryptococcosis can occur as a primary or opportunistic infection and develops as an acute, subacute, or chronic systemic infection involving different organs of the host. Given the limited therapeutic options and the occasional resistance to fluconazole, there is a need to develop novel drugs...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: de Sá, Nívea Pereira, de Lima, Caroline Miranda, Lino, Cleudiomar Inácio, Barbeira, Paulo Jorge Sanches, Baltazar, Ludmila de Matos, Santos, Daniel Assis, de Oliveira, Renata Barbosa, Mylonakis, Eleftherios, Fuchs, Beth Burgwyn, Johann, Susana
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
Assuntos:
Mechanisms of Action: Physiological Effects
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5527588/
https://ncbi.nlm.nih.gov/pubmed/28533240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02700-16
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