Differential Senescence in Feto-Maternal Tissues During Mouse Pregnancy

BACKGROUND: Human studies show that fetal membranes have a limited lifespan and undergo telomere-dependent cellular senescence that is augmented by oxidative stress and mediated by p38 mitogen activated protein kinase (MAPK). Further, these studies suggest that fetal membranes are anatomically physi...

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Udgivet i:Placenta
Main Authors: Bonney, Elizabeth A, Krebs, Kendall, Saade, George, Kechichian, Talar, Trivedi, Jayshil, Huaizhi, Yin, Menon, Ramkumar
Format: Artigo
Sprog:Inglês
Udgivet: 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5527294/
https://ncbi.nlm.nih.gov/pubmed/27324096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.placenta.2016.04.018
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