Natural variation of macrophage activation as disease-relevant phenotype predictive of inflammation and cancer survival

Although mouse models exist for many immune-based diseases, the clinical translation remains challenging. Most basic and translational studies utilize only a single inbred mouse strain. However, basal and diseased immune states in humans show vast inter-individual variability. Here, focusing on macr...

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Bibliographic Details
Published in:Nat Commun
Main Authors: Buscher, Konrad, Ehinger, Erik, Gupta, Pritha, Pramod, Akula Bala, Wolf, Dennis, Tweet, George, Pan, Calvin, Mills, Charles D., Lusis, Aldons J., Ley, Klaus
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2017
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5527282/
https://ncbi.nlm.nih.gov/pubmed/28737175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms16041
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