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Count-based size-correction analysis of maternal plasma DNA for improved noninvasive prenatal detection of fetal trisomies 13, 18, and 21

Purpose: Our goal was to derive more sensitive and accurate Z-scores based on combined DNA count- and size-based algorithms to advance molecular diagnostics for noninvasive prenatal testing of fetal trisomies. Methods: We included 180 cases at high risk for fetal aneuploidy who underwent amniotic fl...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Am J Transl Res
Egile Nagusiak: Zhang, Li, Zhu, Qian, Wang, He, Liu, Shanling
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: e-Century Publishing Corporation 2017
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5527261/
https://ncbi.nlm.nih.gov/pubmed/28804563
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