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Count-based size-correction analysis of maternal plasma DNA for improved noninvasive prenatal detection of fetal trisomies 13, 18, and 21
Purpose: Our goal was to derive more sensitive and accurate Z-scores based on combined DNA count- and size-based algorithms to advance molecular diagnostics for noninvasive prenatal testing of fetal trisomies. Methods: We included 180 cases at high risk for fetal aneuploidy who underwent amniotic fl...
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| 發表在: | Am J Transl Res |
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| Main Authors: | , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
e-Century Publishing Corporation
2017
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5527261/ https://ncbi.nlm.nih.gov/pubmed/28804563 |
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