Terminal Deoxynucleotidyl Transferase (TdT) Inhibiti on of Cord Blood Derived B and T Cells Expansion

Purpose: Terminal deoxynucleotidyl transferase(TdT) is a DNA polymerase that is present in immature pre-B and pre-T cells. TdT inserts N-nucleotides to the V (D) J gene segment during rearrangements of genes, therefore, it plays a vital role in the development and variation of the immune system in v...

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Publicat a:Adv Pharm Bull
Autors principals: Gholami, Sanaz, Mohammadi, Seyede Momeneh, Movasaghpour Akbari, Aliakbar, Abedelahi, Ali, Alihemmati, Alireza, Fallahi, Shirin, Nozad Charoudeh, Hojjatollah
Format: Artigo
Idioma:Inglês
Publicat: Tabriz University of Medical Sciences 2017
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5527235/
https://ncbi.nlm.nih.gov/pubmed/28761823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15171/apb.2017.026
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