Deinococcus radiodurans Toxin–Antitoxin MazEF-dr Mediates Cell Death in Response to DNA Damage Stress

Here we identified a functional MazEF-dr system in the exceptionally stress-resistant bacterium D. radiodurans. We showed that overexpression of the toxin MazF-dr inhibited the growth of Escherichia coli. The toxic effect of MazF-dr was due to its sequence-specific endoribonuclease activity on RNAs...

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Bibliografiske detaljer
Udgivet i:Front Microbiol
Main Authors: Li, Tao, Weng, Yulan, Ma, Xiaoqiong, Tian, Bing, Dai, Shang, Jin, Ye, Liu, Mengjia, Li, Jiulong, Yu, Jiangliu, Hua, Yuejin
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2017
Fag:
Microbiology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5526972/
https://ncbi.nlm.nih.gov/pubmed/28798741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2017.01427
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