Human liver chimeric mouse model based on diphtheria toxin-induced liver injury

AIM: To establish an inducible liver injury mouse model and transplant human hepatocytes to obtain liver-humanized mice. METHODS: We crossed three mouse strains, including albumin (Alb)-cre transgenic mice, inducible diphtheria toxin receptor (DTR) transgenic mice and severe combined immune deficien...

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Bibliographic Details
Published in:World J Gastroenterol
Main Authors: Ren, Xiao-Nan, Ren, Rong-Rong, Yang, Hua, Qin, Bo-Yin, Peng, Xiu-Hua, Chen, Li-Xiang, Li, Shun, Yuan, Meng-Jiao, Wang, Chao, Zhou, Xiao-Hui
Format: Artigo
Language:Inglês
Published: Baishideng Publishing Group Inc 2017
Subjects:
Basic Study
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5526763/
https://ncbi.nlm.nih.gov/pubmed/28785147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v23.i27.4935
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