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A systematic evaluation of methods for tailoring genome-scale metabolic models

Genome-scale models of metabolism can illuminate the molecular basis of cell phenotypes. Since many enzymes are only active in specific cell types, several algorithms use omics data to construct cell line- and tissue-specific metabolic models from genome-scale models. However, these methods have not...

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Dettagli Bibliografici
Pubblicato in:Cell Syst
Autori principali: Opdam, Sjoerd, Richelle, Anne, Kellman, Benjamin, Li, Shanzhong, Zielinski, Daniel C., Lewis, Nathan E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5526624/
https://ncbi.nlm.nih.gov/pubmed/28215528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cels.2017.01.010
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