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A high-throughput screening assay using a photoconvertable protein for identifying inhibitors of transcription, translation, or proteasomal degradation

Dysregulated transcription, translation, and protein degradation are common features of cancer cells, regardless of specific genetic profiles. Several clinical anticancer agents take advantage of this characteristic vulnerability, and interfere with the processes of transcription and translation, or...

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Библиографические подробности
Опубликовано в: :SLAS Discov
Главные авторы: Heidary, David K., Fox, Ashley, Richards, Chris I., Glazer, Edith C.
Формат: Artigo
Язык:Inglês
Опубликовано: 2017
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5526623/
https://ncbi.nlm.nih.gov/pubmed/28328316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/2472555216684333
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