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A high-throughput screening assay using a photoconvertable protein for identifying inhibitors of transcription, translation, or proteasomal degradation

Dysregulated transcription, translation, and protein degradation are common features of cancer cells, regardless of specific genetic profiles. Several clinical anticancer agents take advantage of this characteristic vulnerability, and interfere with the processes of transcription and translation, or...

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Detalhes bibliográficos
Publicado no:SLAS Discov
Main Authors: Heidary, David K., Fox, Ashley, Richards, Chris I., Glazer, Edith C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5526623/
https://ncbi.nlm.nih.gov/pubmed/28328316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/2472555216684333
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