Decreased Rhes mRNA levels in the brain of patients with Parkinson’s disease and MPTP-treated macaques

In rodent and human brains, the small GTP-binding protein Rhes is highly expressed in virtually all dopaminoceptive striatal GABAergic medium spiny neurons, as well as in large aspiny cholinergic interneurons, where it is thought to modulate dopamine-dependent signaling. Consistent with this knowled...

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Udgivet i:PLoS One
Main Authors: Napolitano, Francesco, Booth Warren, Emily, Migliarini, Sara, Punzo, Daniela, Errico, Francesco, Li, Qin, Thiolat, Marie-Laure, Vescovi, Angelo Luigi, Calabresi, Paolo, Bezard, Erwan, Morelli, Micaela, Konradi, Christine, Pasqualetti, Massimo, Usiello, Alessandro
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2017
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5526584/
https://ncbi.nlm.nih.gov/pubmed/28742811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0181677
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