Mendelian Randomization Implicates High-Density Lipoprotein Cholesterol–Associated Mechanisms in Etiology of Age-Related Macular Degeneration

PURPOSE: Undertake a systematic investigation into associations between genetic predictors of lipid fractions and age-related macular degeneration (AMD) risk. DESIGN: Two-sample Mendelian randomization investigation using published data. PARTICIPANTS: A total of 33 526 individuals (16 144 cases, 17 ...

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Vydáno v:Ophthalmology
Hlavní autoři: Burgess, Stephen, Davey Smith, George
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2017
Témata:
Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5526457/
https://ncbi.nlm.nih.gov/pubmed/28456421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ophtha.2017.03.042
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