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The Senescence-Associated Secretory Phenotype: Critical Effector in Skin Cancer and Aging

Cellular senescence, a state of stable cell cycle arrest in response to cellular stress, is an indispensable mechanism to counter tumorigenesis by halting the proliferation of damaged cells. However, through the secretion of an array of diverse cytokines, chemokines, growth factors, and proteases kn...

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Detalhes bibliográficos
Publicado no:J Invest Dermatol
Main Authors: Ghosh, Kanad, Capell, Brian C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5526201/
https://ncbi.nlm.nih.gov/pubmed/27543988
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jid.2016.06.621
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