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A Phase II trial of pembrolizumab for patients with melanoma or non-small cell lung cancer and untreated brain metastases

BACKGROUND: Immunotherapy targeting the PD-1 axis has activity in several tumor types. We aimed to determine the efficacy and safety of pembrolizumab in patients with untreated brain metastases. Here we present results from a Phase II trial of the PD-1 inhibitor pembrolizumab in patients with new or...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Lancet Oncol
Main Authors: Goldberg, Sarah B., Gettinger, Scott N., Mahajan, Amit, Chiang, Anne C., Herbst, Roy S., Sznol, Mario, Tsiouris, Apostolos John, Cohen, Justine, Vortmeyer, Alexander, Jilaveanu, Lucia, Yu, James, Hegde, Upendra, Speaker, Stephanie, Madura, Matthew, Ralabate, Amanda, Rivera, Angel, Rowen, Elin, Gerrish, Heather, Yao, Xiaopan, Chiang, Veronica, Kluger, Harriet M.
פורמט: Artigo
שפה:Inglês
יצא לאור: 2016
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC5526047/
https://ncbi.nlm.nih.gov/pubmed/27267608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S1470-2045(16)30053-5
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