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Cell mutants defective in synthesizing a heparan sulfate proteoglycan with regions of defined monosaccharide sequence.

We have demonstrated that mouse LTA cells synthesize cell-surface heparan sulfate proteoglycans (HSPGs) with regions of defined monosaccharide sequence that specifically interact with antithrombin (HSPGact). It remains unclear how HSPGact can be generated by a biosynthetic pathway with no simple tem...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: De Agostini, A L, Lau, H K, Leone, C, Youssoufian, H, Rosenberg, R D
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1990
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC55258/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2263629/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.87.24.9784
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