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Real-time reverse transcription PCR-based sequencing-independent pathotyping of Eurasian avian influenza A viruses of subtype H7

Low pathogenic avian influenza viruses (LPAIV) of the subtypes H5 and H7 are known to give rise to highly pathogenic (HP) phenotypes by spontaneous insertional mutations which convert a monobasic trypsin-sensitive endoproteolytical cleavage site (CS) within the hemagglutinin (HA) protein into a poly...

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Bibliografiske detaljer
Udgivet i:Virol J
Main Authors: Graaf, Annika, Beer, Martin, Harder, Timm
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5525275/
https://ncbi.nlm.nih.gov/pubmed/28738896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12985-017-0808-3
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