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Preventive effect of celecoxib use against cancer progression and occurrence of oral squamous cell carcinoma

Overexpression of cyclooxygenase-2 in oral cancer increases lymph node metastasis and is associated with a poor prognosis. The potential of celecoxib (CXB) use is reported in cancer treatment by inhibiting proliferation through apoptosis, but the effects on the epithelial-mesenchymal transition (EMT...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Chiang, Shang-Lun, Velmurugan, Bharath Kumar, Chung, Chia-Min, Lin, Shu-Hui, Wang, Zhi-Hong, Hua, Chun-Hung, Tsai, Ming-Hsui, Kuo, Tzer-Min, Yeh, Kun-Tu, Chang, Pei-Ying, Yang, Yi-Hsin, Ko, Ying-Chin
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5524966/
https://ncbi.nlm.nih.gov/pubmed/28740192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-06673-3
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