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Mechanically stable fibrin scaffolds promote viability and induce neurite outgrowth in neural aggregates derived from human induced pluripotent stem cells

Recent work demonstrated that 3D fibrin scaffolds function as an effective substrate for engineering tissues from pluripotent stem cells. However, the rapid degradation rate of fibrin remains a major limitation when differentiating human pluripotent stem cells for tissue engineering applications. Th...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Robinson, Meghan, Douglas, Sarah, Michelle Willerth, Stephanie
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5524903/
https://ncbi.nlm.nih.gov/pubmed/28740258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-06570-9
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