Reduced expression of the murine HLA-G homolog Qa-2 is associated with malignancy, epithelial-mesenchymal transition and stemness in breast cancer cells

Qa-2 is believed to mediate a protective immune response against cancer; however, little is known about the role of Qa-2 in tumorigenesis. Here, we used 4T1 breast cancer cells to study the involvement of Qa-2 in tumor progression in a syngeneic host. Qa-2 expression was reduced during in vivo tumor...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: da Silva, Istéfani L., Montero-Montero, Lucía, Martín-Villar, Ester, Martin-Pérez, Jorge, Sainz, Bruno, Renart, Jaime, Toscano Simões, Renata, Soares Veloso, Émerson, Salviano Teixeira, Cláudia, de Oliveira, Mônica C., Ferreira, Enio, Quintanilla, Miguel
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5524840/
https://ncbi.nlm.nih.gov/pubmed/28740236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-06528-x
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