Human Zika infection induces a reduction of IFN-γ producing CD4 T-cells and a parallel expansion of effector Vδ2 T-cells

The definition of the immunological response to Zika (ZIKV) infection in humans represents a key issue to identify protective profile useful for vaccine development and for pathogenesis studies. No data are available on the cellular immune response in the acute phase of human ZIKV infection, and its...

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Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Cimini, Eleonora, Castilletti, Concetta, Sacchi, Alessandra, Casetti, Rita, Bordoni, Veronica, Romanelli, Antonella, Turchi, Federica, Martini, Federico, Tumino, Nicola, Nicastri, Emanuele, Corpolongo, Angela, Di Caro, Antonino, Kobinger, Gary, Zumla, Alimuddin, Capobianchi, Maria Rosaria, Ippolito, Giuseppe, Agrati, Chiara
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2017
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5524759/
https://ncbi.nlm.nih.gov/pubmed/28740159
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-06536-x
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