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The Tnfaip8-PE complex is a novel upstream effector in the anti-autophagic action of insulin

Defective hepatic autophagy is observed in obesity and diabetes, whereas autophagy is inhibited by insulin in hepatocytes. Insulin-induced anti-autophagy is mediated by non-canonical Gαi3 signaling via an unknown mechanism. Previously, we identified the anti-autophagic activity of Tnfaip8 via activa...

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Detalles Bibliográficos
Publicado en:Sci Rep
Main Authors: Kim, Ji-Soo, Park, Jimin, Kim, Mi-Sun, Ha, Ji-Young, Jang, Ye-Won, Shin, Dong Hae, Son, Jin H.
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5524748/
https://ncbi.nlm.nih.gov/pubmed/28740220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-06576-3
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