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The resident pathobiont Staphylococcus xylosus in Nfkbiz-deficient skin accelerates spontaneous skin inflammation

IκBζ, which is encoded by the Nfkbiz gene, is a member of the nuclear IκB family of proteins that act as transcriptional regulators via association with NF-κB. Nfkbiz-deficient (Nfkbiz (−/−)) mice develop spontaneous dermatitis; however, the underlying mechanism has yet to be elucidated. In our stud...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Sci Rep
Hauptverfasser: Kim, Yeji, Lee, Yong-Soo, Yang, Jin-Young, Lee, Su-Hyun, Park, Yun-Yong, Kweon, Mi-Na
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5524713/
https://ncbi.nlm.nih.gov/pubmed/28740238
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-05740-z
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