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Spatial cycles mediated by UNC119 solubilisation maintain Src family kinases plasma membrane localisation

The peripheral membrane proto-oncogene Src family protein tyrosine kinases relay growth factor signals to the cytoplasm of mammalian cells. We unravel the spatial cycles of solubilisation, trapping on perinuclear membrane compartments and vesicular transport that counter entropic equilibration to en...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Konitsiotis, Antonios D., Roßmannek, Lisaweta, Stanoev, Angel, Schmick, Malte, Bastiaens, Philippe I. H.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5524651/
https://ncbi.nlm.nih.gov/pubmed/28740133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-00116-3
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