The Dkk3 gene encodes a vital intracellular regulator of cell proliferation

Members of the Dickkopf (Dkk) family of Wnt antagonists interrupt Wnt-induced receptor assembly and participate in axial patterning and cell fate determination. One family member, DKK3, does not block Wnt receptor activation. Loss of Dkk3 expression in cancer is associated with hyperproliferation an...

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Veröffentlicht in:PLoS One
Hauptverfasser: Leonard, Jack L., Leonard, Deborah M., Wolfe, Scot A., Liu, Jilin, Rivera, Jaime, Yang, Michelle, Leonard, Ryan T., Johnson, Jacob P. S., Kumar, Prashant, Liebmann, Kate L., Tutto, Amanda A., Mou, Zhongming, Simin, Karl J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2017
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5524345/
https://ncbi.nlm.nih.gov/pubmed/28738084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0181724
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