The N-terminal region of serum amyloid A3 protein activates NF-κB and up-regulates MUC2 mucin mRNA expression in mouse colonic epithelial cells

Serum amyloid A (SAA) is the major acute-phase protein and a precursor of amyloid A (AA) in AA amyloidosis in humans and animals. SAA isoforms have been identified in a wide variety of animals, such as SAA1, SAA2, SAA3, and SAA4 in mouse. Although the biological functions of SAA isoforms are not com...

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Dettagli Bibliografici
Pubblicato in:PLoS One
Autori principali: Tashiro, Manami, Iwata, Ami, Yamauchi, Marika, Shimizu, Kaori, Okada, Ayaka, Ishiguro, Naotaka, Inoshima, Yasuo
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2017
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5524290/
https://ncbi.nlm.nih.gov/pubmed/28738073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0181796
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