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Parkin overexpression protects retinal ganglion cells against glutamate excitotoxicity

PURPOSE: To investigate the role of parkin in regulating mitochondrial homeostasis of retinal ganglion cells (RGCs) under glutamate excitotoxicity. METHODS: Rat RGCs were purified from dissociated retinal tissue with a modified two-step panning protocol. Cultured RGCs were transfected with parkin us...

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Библиографические подробности
Опубликовано в: :Mol Vis
Главные авторы: Hu, Xinxin, Dai, Yi, Sun, Xinghuai
Формат: Artigo
Язык:Inglês
Опубликовано: Molecular Vision 2017
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5524269/
https://ncbi.nlm.nih.gov/pubmed/28761318
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