Two Decades of Cardiovascular Trials With Primary Surrogate Endpoints: 1990–2011

BACKGROUND: Surrogate endpoint trials test strategies more efficiently but are accompanied by uncertainty about the relationship between changes in surrogate markers and clinical outcomes. METHODS AND RESULTS: We identified cardiovascular trials with primary surrogate endpoints published in the New...

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Detalhes bibliográficos
Publicado no:J Am Heart Assoc
Main Authors: Bikdeli, Behnood, Punnanithinont, Natdanai, Akram, Yasir, Lee, Ike, Desai, Nihar R., Ross, Joseph S., Krumholz, Harlan M.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5524035/
https://ncbi.nlm.nih.gov/pubmed/28325713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.116.005285
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