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HAND2 Target Gene Regulatory Networks Control Atrioventricular Canal and Cardiac Valve Development

The HAND2 transcriptional regulator controls cardiac development and we uncover additional essential functions in the endothelial to mesenchymal transition (EMT) underlying cardiac cushion development in the atrioventricular canal (AVC). In Hand2-deficient mouse embryos, the EMT underlying AVC cardi...

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Detalles Bibliográficos
Publicado en:Cell Rep
Main Authors: Laurent, Frédéric, Girdziusaite, Ausra, Gamart, Julie, Barozzi, Iros, Osterwalder, Marco, Akiyama, Jennifer A., Lincoln, Joy, Lopez-Rios, Javier, Visel, Axel, Zuniga, Aimée, Zeller, Rolf
Formato: Artigo
Idioma:Inglês
Publicado: 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5523860/
https://ncbi.nlm.nih.gov/pubmed/28538179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2017.05.004
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