Brefeldin A enhances docetaxel-induced growth inhibition and apoptosis in prostate cancer cells in monolayer and 3D cultures

Docetaxel is a commonly used chemotherapeutic drug for patients with late stage prostate cancer. However, serious side effect and drug resistance limit its clinical success. Brefeldin A is a 16-membered macrolide antibiotic from mangrove-derived Fungus Aspergillus sp. (9Hu), which exhibited potent c...

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Publicado en:Bioorg Med Chem Lett
Autores principales: Huang, Huarong, Liu, Ting, Guo, Junxi, Yu, Lin, Wu, Xiaofeng, He, Yan, Li, Dongli, Liu, Junlei, Zhang, Kun, Zheng, Xi, Goodin, Susan
Formato: Artigo
Lenguaje:Inglês
Publicado: 2017
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5523854/
https://ncbi.nlm.nih.gov/pubmed/28462831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2017.04.047
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