Alterations of Clock Gene RNA Expression in Brain Regions of a Triple Transgenic Model of Alzheimer’s Disease

A disruption to circadian rhythmicity and the sleep/wake cycle constitutes a major feature of Alzheimer’s disease (AD). The maintenance of circadian rhythmicity is regulated by endogenous clock genes and a number of external Zeitgebers, including light. This study investigated the light induced chan...

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Veröffentlicht in:J Alzheimers Dis
Hauptverfasser: Bellanti, Francesco, Iannelli, Giuseppina, Blonda, Maria, Tamborra, Rosanna, Villani, Rosanna, Romano, Adele, Calcagnini, Silvio, Mazzoccoli, Gianluigi, Vinciguerra, Manlio, Gaetani, Silvana, Giudetti, Anna Maria, Vendemiale, Gianluigi, Cassano, Tommaso, Serviddio, Gaetano
Format: Artigo
Sprache:Inglês
Veröffentlicht: IOS Press 2017
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5523844/
https://ncbi.nlm.nih.gov/pubmed/28671110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-160942
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