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The IDO–AhR Axis Controls Th17/Treg Immunity in a Pulmonary Model of Fungal Infection

In infectious diseases, the enzyme indoleamine 2,3 dioxygenase-1 (IDO1) that catalyzes the tryptophan (Trp) degradation along the kynurenines (Kyn) pathway has two main functions, the control of pathogen growth by reducing available Trp and immune regulation mediated by the Kyn-mediated expansion of...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: de Araújo, Eliseu Frank, Feriotti, Claudia, Galdino, Nayane Alves de Lima, Preite, Nycolas Willian, Calich, Vera Lúcia Garcia, Loures, Flávio Vieira
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5523665/
https://ncbi.nlm.nih.gov/pubmed/28791025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.00880
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