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Recombinant Tula hantavirus shows reduced fitness but is able to survive in the presence of a parental virus: analysis of consecutive passages in a cell culture

Tula hantavirus carrying recombinant S RNA segment (recTULV) grew in a cell culture to the same titers as the original cell adapted variant but presented no real match to the parental virus. Our data showed that the lower competitiveness of recTULV could not be increased by pre-passaging in the cell...

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Autors principals: Plyusnina, Angelina, Plyusnin, Alexander
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2005
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC552329/
https://ncbi.nlm.nih.gov/pubmed/15725355
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1743-422X-2-12
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