The small heat-shock proteins IbpA and IbpB reduce the stress load of recombinant Escherichia coli and delay degradation of inclusion bodies

BACKGROUND: The permanently impaired protein folding during recombinant protein production resembles the stress encountered at extreme temperatures, under which condition the putative holding chaperones, IbpA/IbpB, play an important role. We evaluated the impact of ibpAB deletion or overexpression o...

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Main Authors: LeThanh, Ha, Neubauer, Peter, Hoffmann, Frank
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2005
Assuntos:
Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC552319/
https://ncbi.nlm.nih.gov/pubmed/15707488
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2859-4-6
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