Cholangiocarcinoma stem-like subset shapes tumor-initiating niche by educating associated macrophages

BACKGROUND & AIMS: A therapeutically challenging subset of cells, termed cancer stem cells (CSCs) are responsible for cholangiocarcinoma (CCA) clinical severity. Presence of tumor-associated macrophages (TAMs) has prognostic significance in CCA and other malignancies. Thus, we hypothesized that...

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Bibliographic Details
Published in:J Hepatol
Main Authors: Raggi, Chiara, Correnti, Margherita, Sica, Antonio, Andersen, Jesper B., Cardinale, Vincenzo, Alvaro, Domenico, Chiorino, Giovanna, Forti, Elisa, Glaser, Shannon, Alpini, Gianfranco, Destro, Annarita, Sozio, Francesca, Di Tommaso, Luca, Roncalli, Massimo, Banales, Jesus M., Coulouarn, Cédric, Bujanda, Luis, Torzilli, Guido, Invernizzi, Pietro
Format: Artigo
Language:Inglês
Published: 2016
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5522599/
https://ncbi.nlm.nih.gov/pubmed/27593106
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jhep.2016.08.012
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