MAIT cells accumulate in placental intervillous space and display a highly cytotoxic phenotype upon bacterial stimulation

During pregnancy, the maternal immune system must tolerate the developing foetus, and yet retain a potent antimicrobial response to prevent infections. Mucosal associated invariant T (MAIT) cells recognize microbial-derived vitamin B metabolites presented on the MR1 molecule, but their presence and...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Solders, Martin, Gorchs, Laia, Erkers, Tom, Lundell, Anna-Carin, Nava, Silvia, Gidlöf, Sebastian, Tiblad, Eleonor, Magalhaes, Isabelle, Kaipe, Helen
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5522401/
https://ncbi.nlm.nih.gov/pubmed/28733576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-06430-6
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