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Negative regulation of the rat stromelysin gene promoter by retinoic acid is mediated by an AP1 binding site.

Stromelysin is a member of the metalloproteinase family which plays an important role in extracellular matrix remodelling during many normal and disease processes. We show here that in polyomavirus-transformed rat embryo fibroblast cells (PyT21), the transcription from the stromelysin gene is repres...

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Bibliographic Details
Main Authors: Nicholson, R C, Mader, S, Nagpal, S, Leid, M, Rochette-Egly, C, Chambon, P
Format: Artigo
Language:Inglês
Published: 1990
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC552237/
https://ncbi.nlm.nih.gov/pubmed/2176152
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