NatB-mediated protein N-α-terminal acetylation is a potential therapeutic target in hepatocellular carcinoma

The identification of new targets for systemic therapy of hepatocellular carcinoma (HCC) is an urgent medical need. Recently, we showed that hNatB catalyzes the N-α-terminal acetylation of 15% of the human proteome and that this action is necessary for proper actin cytoskeleton structure and functio...

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Veröffentlicht in:Oncotarget
Hauptverfasser: Neri, Leire, Lasa, Marta, Elosegui-Artola, Alberto, D'Avola, Delia, Carte, Beatriz, Gazquez, Cristina, Alve, Sara, Roca-Cusachs, Pere, Iñarrairaegui, Mercedes, Herrero, Jose, Prieto, Jesús, Sangro, Bruno, Aldabe, Rafael
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2017
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5522283/
https://ncbi.nlm.nih.gov/pubmed/28498797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.17332
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