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Evaluation of (99m)Tc-HYNIC-MPG as a novel SPECT radiotracer to detect EGFR-activating mutations in NSCLC

Tyrosine kinase inhibitors (EGFR-TKIs) targeting the epidermal growth factor receptor (EGFR) have been used in non-small cell lung carcinoma (NSCLC) for years with promising results, in particular in patients with activating mutations in the EGFR kinase domain (exon 19 E746-A750 deletion or exon 21...

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Publicat a:Oncotarget
Autors principals: Xiao, Zunyu, Song, Yan, Kai, Wang, Sun, Xilin, Shen, Baozhong
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5522229/
https://ncbi.nlm.nih.gov/pubmed/28489575
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.17251
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