Lysophosphatidic acid (LPA) as a pro-fibrotic and pro-oncogenic factor: a pivotal target to improve the radiotherapy therapeutic index

Radiation-induced fibrosis is widely considered as a common but forsaken phenomenon that can lead to clinical sequela and possibly vital impairments. Lysophosphatidic acid is a bioactive lipid involved in fibrosis and probably in radiation-induced fibrosis as suggested in recent studies. Lysophospha...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Rancoule, Chloé, Espenel, Sophie, Trone, Jane-Chloé, Langrand-Escure, Julien, Vallard, Alexis, Rehailia-Blanchard, Amel, Hamrouni, Anis El Meddeb, Xia, Yaxiong, Guy, Jean-Baptiste, Ben-Mrad, Majed, Magné, Nicolas
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Review
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5522168/
https://ncbi.nlm.nih.gov/pubmed/28402936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.16672
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