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ABCG2 downregulation in glioma stem cells enhances the therapeutic efficacy of demethoxycurcumin
We analyzed the role of ABCG2, a drug transporter, in determining the sensitivity of glioma stem cells (GSCs) to demethoxycurcumin (DMC). We first demonstrated that ABCG2 is more highly expressed in GSCs than primary astrocytes. Modulation of ABCG2 levels in GSCs by transfection of ABCG2 shRNA or a...
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| Publicado no: | Oncotarget |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Impact Journals LLC
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5522142/ https://ncbi.nlm.nih.gov/pubmed/28591733 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.18018 |
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