Self-assembling nanoparticles encapsulating zoledronic acid inhibit mesenchymal stromal cells differentiation, migration and secretion of proangiogenic factors and their interactions with prostate cancer cells

Zoledronic Acid (ZA) rapidly concentrates into the bone and reduces skeletal-related events and pain in bone metastatic prostate cancer (PCa), but exerts only a limited or absent impact as anti-cancer activity. Recently, we developed self-assembling nanoparticles (NPS) encapsulating zoledronic acid...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Borghese, Cinzia, Casagrande, Naike, Pivetta, Eliana, Colombatti, Alfonso, Boccellino, Mariarosaria, Amler, Evzen, Normanno, Nicola, Caraglia, Michele, De Rosa, Giuseppe, Aldinucci, Donatella
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5522116/
https://ncbi.nlm.nih.gov/pubmed/28477013
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.17216
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